Does Rybelsus help with weight loss Although Rybelsus is not a weight loss drug many people lose weight while taking itPeople lost on average five pounds kg while taking Rybelsus mg and pounds kg while taking Rybelsus mgOne of the ways Rybelsus works is by helping to make you feel full after a mealRybelsus semaglutide is an oral medicine that is used to improve blood sugar control in adults over the age of with type diabetes It may be prescribed as firstline therapy in addition to diet and exercise or in addition to other medications typically used for type diabetesWeight losses of kg to kg may occur in people taking Rybelsus for type diabetes Research has shown that after weeks people lost an average of pounds kg while taking Rybelsus mg pounds kg while taking Rybelsus mgPeople with a higher initial body weight and those experiencing more digestive symptoms may be more likely to lose weight once treatment with Rybelsus has startedRybelsus is not used to treat type diabetesRelated questions Tirzepatide vs semaglutide How do they compare How does semaglutide work for weight loss Why am I not losing weight on Ozempic How does Rybelsus workRybelsus belongs to a class of medicines called GLP receptor agonists It may also be called an incretin mimeticRybelsus works by mimicking the functions of natural incretin hormones in the body that help keep blood sugar levels under control especially immediately following a mealIncretin hormones are gut peptides that are secreted from the stomach when food is eaten They also stimulate the secretion of insulin in response to high blood glucose levels Two incretin hormones are known as GIP glucosedependent insulinotropic polypeptide and GLP glucagonlike peptideIn people with type diabetes natural incretin release is diminished or no longer present However it can be stimulated with pharmacological agents such as RybelsusRybelsus shares of the same structure as human GLP but is manmade It acts like GLP and binds to GLP receptors stimulating insulin release from the pancreas reducing the amount of glucagon secreted by the liver and makes a person feel full by slowing gastric emptying